- WHAT IT DOES -
 
 

Assists in the Breakdown of Fat *

What does it do? 

Methionine is one of the essential amino acids (building blocks of protein). It supplies sulfur and other compounds required by the body for normal metabolism and growth. Methionine also belongs to a group of compounds called lipotropics; others in this group include choline, inositol, and betaine.

Persons with AIDS have low levels of methionine. Some researchers suggest that this may explain some aspects of the disease process,1 2 3 especially the deterioration that occurs in the nervous system that can cause symptoms including dementia.4 5 A preliminary study has suggested that methionine (6 grams per day) may improve memory recall in persons with AIDS-related nervous system degeneration.6

Other preliminary studies have suggested that methionine (5 grams per day) may help treat some symptoms of Parkinson’s disease.7

Methionine (2 grams per day) in combination with several antioxidants, reduced pain and recurrences of attacks of pancreatitis in a small but well-controlled trial.8

 

 
 
- PRODUCT DESCRIPTION -
 
 


L-METHIONINE FREE FORM AMINO ACID 500
L-Methionine is an essential sulfur-bearing amino acid. In the body, it converts to L-Cysteine and therefore is potentially beneficial in liver detoxification and in neutralizing toxins.* It has been shown to support healthy copper and lead serum levels.* L-Methionine is considered important for liver fat metabolism, healthy skin and nails, and energy production.* High purity, well tolerated, hypoallergenic*

METHIONINE is an essential amino acid that is not synthesized by the body and must be obtained from food. It is one of the sulphur containing amino acids and is important in many body functions. Through its supply of sulphur, it improves the tone and pliability of the skin, conditions the hair and strengthens nails. The mineral sulphur also protects the cells from airborne pollutants, such as smog, slows down the aging process in the cells, and is involved with the production of protein. Methionine is essential for the absorption and transportation and bioavailability of selenium and zinc in the body. It also acts as a lipotropic agent to prevent excess fat buildup in the liver, and is an excellent chelator of heavy metals, such as lead, cadmium and mercury, binding them and aiding in their excretion from the body.

It can help fatigue and may be useful in some cases of allergy because it reduces histamine release. It has also been used in the treatment of rheumatic fever and toxemia resulting from pregnancy. Recent studies show methionine deficiencies may be associated with the development of age related cataracts, and supplements may delay their development. In Parkinson's disease patients taking L-Dopa, it was found that additional supplements with L-Methionine may further decrease the tremors and rigidity that limit normal activities.

The best food sources are beef, chicken, fish, pork, soybeans, eggs, cottage cheese, liver, sardines, yogurt, pumpkin seeds, sesame seeds and lentils. The range of human need for methionine is estimated at between 800 and 3,000 milligrams per day. This represents a 3.7 fold variation, based on a sample of 29 individuals

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any diseas


 
 
- Q & A -
 
 

 

Where is it found? 

Meat, fish, and dairy are all good sources of methionine.

Who is likely to be deficient?

 Most people consume plenty of methionine through a typical diet. Lower intakes during pregnancy have been associated with neural tube defects in newborns, but the significance of this is not yet clear.9

How much is usually taken? 

Amino acid requirements vary according to body weight; however, average-size adults require approximately 800–1,000 mg of methionine per day—an amount exceeded by most Western diets. Therefore, most people would not benefit from methionine supplementation.

Are there any side effects or interactions? 

Animal studies suggest that diets high in methionine, in the presence of B vitamin deficiencies, may increase the risk for atherosclerosis (hardening of the arteries) by increasing blood levels of cholesterol and a compound called homocysteine.10 This idea has not yet been tested in humans. Excessive methionine intake, in the presence of inadequate intake of folic acid, vitamin B6, and vitamin B12, can increase the conversion of methionine to homocysteine—a substance linked to heart disease and stroke. However, whether this relationship creates a significant hazard for humans taking supplemental methionine has not been established. Supplementation of up to 2 grams methionine daily for long periods of time has not produced any serious side effects.11

At the time of writing, there were no well-known drug interactions with methionine.

 

References:

1. Muller F et al. Elevated plasma concentration of reduced homocysteine in patients with Human Immunodeficiency Virus infection. Am J Clin Nutr 1996;242–46.
2. Revillard JP. Lipid peroxidation in Human Immunodeficiency Virus infection. J Acquired Immunodef Synd 1992;5:637–38.
3. Singer P et al. Nutritional aspects of the Acquired Immunodeficiency Syndrome. Am J Gastroenterol 1992;87:265–73.
4. Tan SV, Guiloff RJ. Hypothesis on the pathogenesis of vacuolar myelopathy, dementia, and peripheral neuropathy in AIDS. J Neurol Neurosurg Psychiat 1998 65:23–28.
5. Keating JN et al. Evidence of brain methyltransferase inhibition and early brain involvement in HIV-positive patients. Lancet 1991;337:935–39.
6. Dorfman D, DiRocco A, Simpson D, et al. Oral methionine may improve neuropsychological function in patients with AIDS myelopathy: results of an open-label trial. AIDS 1997;11:1066–67.
7. Smythies JR, Halsey JH. Treatment of Parkinson’s disease with l-methionine. South Med J 1984;77:1577.
8. Uden S, Bilton D, Nathan L, et al. Antioxidant therapy for recurrent pancreatitis: placebo-controlled trial. Aliment Pharmacol Ther 1990;4:357–71.
9. Shaw GM, Velie EM, Schaffer DM. Is dietary intake of methionine associated with a reduction in risk for neural tube defect-associated pregnancies? Teratology 1997;56:295–99.
10. Toborek M, Hennig B. Is methionine an atherogenic amino acid? J Optimalt Nutr 1994;3(2):80–83.
11. Leach FN, Braganza JM. Methionine is important in treatment of chronic pancreatitis. Br Med J 1998;316:474 [letter].

 

 
 
- TECHNICAL SPECIFICATIONS -
 
 


Other Ingredients: Silica, Magnesium Stearate, Gelatin.

Contains no: yeast, wheat, gluten, corn, soy, egg, milk.

Suggested Use: As a dietary supplement, take 1 capsule one or more times daily as needed. Take with juice or water, preferably between meals.


Warnings:
Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licenced physician and/or pharmacist prior to taking dietary supplements. KEEP OUT OF THE REACH OF CHILDREN. Keep container tightly closed in a cool, dry and dark place. Do not eat freshness packet. Keep in bottle.

 

 

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